GNU Collaborative International Dictionary of English
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Found one definition
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Irk (ẽrk), v. t. [OE. irken to tire, become tired; cf. Sw. yrka to urge, enforce, press, or G. ekel disgust, MHG. erklich disgusting; perh. akin to L. urgere to urge, E. urge.] To weary; to give pain; to annoy.
[1913 Webster]
To see this sight, it irks my very soul. Shak.
[1913 Webster]
It irketh him to be here. M. Arnold.
[1913 Webster]