GNU Collaborative International Dictionary of English
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Found one definition
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Spay (?), v. t. [imp. & p. p. Spayed (?); p. pr. & vb. n. Spaying.] [Cf. Armor. spac'hein, spaza to geld, W. dyspaddu to geld, L. spado a eunuch, Gr. >.] To remove or extirpate the ovaries of, as a sow or a bitch; to castrate (a female animal).
[1913 Webster]