GNU Collaborative International Dictionary of English

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Found one definition

1.       
   moleskin (mōlˈskĭn), n.
   1. Any fabric having a thick soft shag, like the fur of a mole; esp., a kind of strong twilled fustian.
   
   [1913 Webster]
   
   
   2. A soft fabric having an adhesive backing, applied to the skin at points susceptible to abrasion, as on the feet, to prevent irritation or blistering during exercise, such as hiking.
   
   [PJC]