GNU Collaborative International Dictionary of English

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Found one definition

1.       
   { Malignance , Malignancy , } n. [See Malignant.]
    The state or quality of being malignant; extreme malevolence; bitter enmity; malice; disposition toward evil; intense ill will; as, malignancy of heart.
   1913 Webster
   Unfavorableness; evil nature.
   1913 Webster
   The malignancy of my fate might perhaps distemner yours.
   Shak.
   
   1913 Webster
   (Med.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever.
   1913 Webster
   Hence: (Med.) A cancerous tumor that is spreading beyond the point of origin.
   Syn. -- malignant tumor, malignant neoplasm, metastatic tumor.
   WordNet 1.5
   The state of being a malignant.
   1913 Webster